Some scholars consider the Saginaw Valley, particularly the vicinity of Flint, to be the oldest continually inhabited part of Michigan. Regardless of the validity of this claim, the region was home to several Ojibwa tribes at the top of the 19th century, with a particularly significant community established near present-day Montrose. The Flint River had several convenient fords which became points of contention among rival tribes, as attested by the presence of arrowheads and burial mounds near Flushing.

The proximity to the Great Lakes keeps the climate more moderate than other cities at similar latitudes. The summers are generally warm and humid, with an average high temperature in the 80's and a record high of 108 set on July 13, 1936. The winters are cold and snowy, with average lows in the teens and a record low of -28 set on February 14, 1916. In the spring it is snowy to start, then stormy and warm through the end of it. In the fall it is cool and breezy with generous amounts of precipitation. The last snowfall of the season comes anywhere in between the middle of April and the beginning of May. The first snowfall of the season usually comes sometime in October. The area is quite cloudy and breezy most of the year. Rainfall in is fairly evenly distributed throughout the year and snowfall is around 45 inches per year.